- What is the recovery time objective?
- A long RTO could mean that rebuild / restoring from tape is viable
- What is the recovery point objective?
- How much can be lost - if you need things current, or within minutes last night's tape backup won't work
- Do you have to have off-site?
- Maybe you only have one data center - could you co-locate? Could an online solution solution such as Acronis or Datto have be viable?
- Do all mailbox databases need to be readily available?
- Do you have VIP users with more sensitive RTO/RPO numbers? This could be a way to cut costs if only some of the data is replicated.
- Do line of business applications require e-mail integration?
- Maybe that document management system running your client data ties into Exchange and your entire business is down if e-mail is down.
- Leverage native capabilities!
- DAGs can extend across multiple sites and provide great resilience against a variety of disasters including point failures such as disk, server, and network or even entire data center failure. (DC failure - that really big point failure!)
These are just a few "big ticket" areas of consideration when planning for HA/DR in an Exchange environment. Starting with these can let you dig into details and begin to prepare options for a client to have a successful e-mail availability and recovery solution.